We had a few "blow out" sales when we moved last summer. We literally sold our entire house. Lots of work. This is what I did:
Furniture and decorative items were staged. I set them up out on the lawn to look like outdoor rooms. I had several people comment on how neat that was and it definitely encouraged people to hang around and check stuff out. I priced things to MoVe, so larger items were individually marked and smaller "like" items (picture frames, vases, knick knacks) were all the same price for each.
Ziploc odd and end items up, staple the tops shut and sell for one price. No opening up and rooting around allowed. Examples would include bags of fabric scraps, kitchen gadgets, garage odd/ends, gardening supplies, small kids toys, socks/undies. Things don't tend to get feet and "walk" that way either, especially little items.
Books/Videos/DVD's should be the same price for all. Don't bother individually pricing them, if they are the same price then people tend to buy more. Also, think about things like, "buy 4, get the 5th free", especially with books.
Clothing, espeically kids stuff, price low! I would sell kids stuff for a quarter a piece. Nicer items such as dresses, jackets, etc for kids hang on hangers and price individually. Let people see how nice they are and include the hanger for free, always a nice selling point.
The last hour or so of my sale, I would sell a bag for a set price and then tell people they could fill it. Kinda like a rummage sale. Pull out anything you don't want included. I would do this only if I was ready to haul it off to Goodwill, not if I was planning on having another sale and including remaining items.